What are the risks and side effects of TIL therapy?

TIL therapy is an intense treatment with some short-term risks from conditioning chemotherapy. These include:

• Low blood counts that may require blood transfusions
• Infections
• Fatigue
• Nausea and vomiting
• Diarrhea
• Hair loss
• Mouth sores

IL-2, which is used to stimulate your TILs, can also cause temporary side effects, including:

• Fever
• Rash
• Low blood pressure
• Abnormal heart rate
• Nausea
• Diarrhea
• Fatigue
• Confusion
• Leg swelling

Your entire team — including your oncologist, nurse practitioner, physician assistant and other clinicians — will closely monitor you for complications throughout your treatment. Because our cancer team has many years of experience treating patients with cell therapies like TIL therapy, we have strategies to minimize these side effects.