Treatment Options for Lymphoma

Blood cancers, including lymphoma, are extremely heterogeneous and can involve a variety of treatment options, often in combination. Some form of chemotherapy, radiation therapy, immunotherapy, or a combination is typically used to treat Hodgkin lymphoma. Bone marrow or stem cell transplantation may also sometimes be done under special circumstances. Most patients with Hodgkin lymphoma live long and healthy lives following successful treatment.

Many people treated for non-Hodgkin lymphoma will receive some form of chemotherapy, radiation therapy, biologic therapy, immunotherapy, or a combination of these. Bone marrow, stem cell transplantation, or CAR T-cell therapy may sometimes be used. Surgery may be used under special circumstances, but primarily to obtain a biopsy for diagnostic purposes.

Although “indolent” or slow-growing forms of non-Hodgkin lymphoma are not currently curable, the prognosis is still very good. Patients may live for 20 years or more following an initial diagnosis. In certain patients with an indolent form of the disease, treatment may not be necessary until there are signs of progression. Response to treatment can also change over time. Treatment that worked initially may be ineffective the next time, making it necessary to always keep abreast of the latest information on new or experimental treatment options.