World’s First! Chinese Tongji Hospital Successfully Treats Immune-Mediated Necrotizing Myopathy with CAR-T Cells!
ππ¬β¨ World’s First! Chinese Tongji Hospital Successfully Treats Immune-Mediated Necrotizing Myopathy with CAR-T Cells! β¨π¬π
πA groundbreaking achievement in medicine! Immune-Mediated Necrotizing Myopathy
Professor Wang Wei’s team from Tongji Hospital, affiliated with Huazhong University of Science and Technology, has brought unprecedented hope to patients with immune-mediated necrotizing myopathy. π
π On January 30th, their research was published in the prestigious journal “Proceedings of the National Academy of Sciences” (PNAS). They utilized CAR-T cells targeting mature B cell antigen (BCMA) for the first time, achieving significant clinical efficacy in treating immune-mediated necrotizing myopathy. This research opens new avenues for treating this condition, marking a historic breakthrough in medicine.
βΉοΈ CAR-T cell therapy
is a gene-editing cellular treatment method. Patient’s own T cells are extracted, genetically modified in vitro to possess targeted killing capabilities. These modified CAR-T cells are then reintroduced into the patient’s body to selectively eliminate target cells, bringing about dramatic changes in the disease’s progression.
π¨ββοΈ Patient Mr. Deng is a successful case of CAR-T cell therapy. Diagnosed with immune-mediated necrotizing myopathy seven and a half years ago, his condition worsened over time, leaving him bedridden. After receiving CAR-T treatment, his health significantly improved, he successfully entered graduate school for medical studies, achieved full recovery, discontinued all immunosuppressive drugs, and now lives medication-free. This is a remarkable victory! πͺ
π What’s even more surprising is that several patients treated with CAR-T cells experienced the regrowth of new B cells approximately one year post-treatment. These new B cells exhibit a completely different phenotype, and pathogenic antibodies in the patients’ bodies completely disappear, achieving a joyful “immune reshaping.”
π This breakthrough research brings hope to autoimmune disease patients worldwide.
Professor Wang Wei’s team’s efforts have paved the way for new treatment approaches, offering a fresh start for patients once deemed untreatable. We look forward to the global adoption of this treatment method, benefiting more patients worldwide. Let’s cheer for this remarkable achievement together! π
In addition to lung cancer, we are currently urgently recruiting patients with B-cell lymphoma, T-cell lymphoma, T-cell leukemia (T-ALL), acute lymphoblastic leukemia, myeloma, and other types of cancer!
You can send electronic copies or photos of genetic testing reports and diagnostic reports to the email address:
doctor.huang@globecancer.com,
or click on the
WhatsApp+8613717959070.
The Medical Department will contact you as soon as they receive the reports.π
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