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Breakthrough Therapy Brings New Hope: Swiss Patient Thomas Begins CAR-T Treatment at Tongji Hospital, Wuhan
**Breakthrough Therapy Brings New Hope: Swiss Patient Thomas Begins CAR-T Treatment at Tongji Hospital, Wuhan**
Professor Li Chunrui’s team at Tongji Hospital in Wuhan successfully conducted a case of chimeric antigen receptor T-cell (CAR-T) immunotherapy for a patient with relapsed and refractory multiple myeloma, offering new life to Swiss patient Thomas.
Thomas, a 54-year-old patient from Switzerland, has been battling multiple myeloma for nearly ten years. Initially diagnosed in 2016, he has endured severe bone pain and undergone multiple rounds of systemic chemotherapy and monoclonal antibody therapy. Although his condition was temporarily controlled, repeated relapses, with the most recent in 2022, made treatment increasingly challenging.
However, the global development of CAR-T therapy has reignited hope. The introduction of FUCASO (Eque-cel), the first fully human CAR-T product in mainland China, has brought new light to Thomas. This groundbreaking treatment not only boasts low immunogenicity but also offers prolonged efficacy, enabling patients to return to a high quality of life.
Thomas ultimately chose to receive the cutting-edge CAR-T therapy at Tongji Hospital, seeking a fundamental breakthrough in his treatment. The apheresis procedure was conducted by the hospital’s top hematology team, who possess international-level expertise and place special emphasis on patient-specific needs and treatment safety. The attending physician elaborated on the apheresis process in an interview, saying, “We precisely collected T-cells from Thomas’s body, then modified these cells in a controlled environment to specifically target multiple myeloma cancer cells. The use of FUCASO greatly enhanced the treatment’s specificity and success rate.”
Thomas expressed high recognition and appreciation for the hospital team’s professionalism and the transparency of the treatment process. Tongji Hospital leveraged its advanced technology and equipment to provide Thomas with a smooth and efficient apheresis experience, ensuring high-quality T-cell collection and paving the way for the subsequent treatment.
Thomas is now filled with confidence and anticipation, looking forward to the new life that CAR-T therapy promises. This new beginning marks a significant step in his treatment journey, injecting new hope into his path to recovery.
We will continue to follow up on the patient’s subsequent treatment and report on the progress.
CART MultipleMyeloma FUCASOJourney Equecel TongjiHospital CancerSurvivor BloodCancer Immunotherapy FullyHumanCART CancerTreatment
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Success Story: Foreign Multiple Myeloma Patient Completes CAR-T Treatment at Chinese Hospital
A foreign multiple myeloma patient successfully completed CAR-T treatment at Jiahui International Hospital and was discharged with promising results.
Jiahui International Hospital
CAR-T therapy
short for “chimeric antigen receptor T-cell therapy,” represents a milestone in individualized cell immunotherapy for human cancers. It involves collecting the patient’s T-cells, genetically modifying them ex vivo to enhance their ability to recognize tumor cells specifically. These engineered “armed” T-cells (CAR-T cells) are then infused back into the patient to target and destroy tumor cells, while also forming memory T-cells for sustained anti-tumor effects. China has approved CAR-T therapy for lymphoma, multiple myeloma, and acute leukemia. The treatment process includes patient screening, bridging therapy, adverse reaction management, and long-term follow-up, requiring close collaboration among various teams, including hematology, cardiology, respiratory medicine, neurology, ICU, and experienced nursing teams.
The patient
an Australian residing in Shanghai, was diagnosed with multiple myeloma in 2008. Despite undergoing various treatments, including chemotherapy, immunotherapy, targeted therapy, and autologous stem cell transplantation, he unfortunately relapsed in 2022 with severe pain and bone damage. But due to the exorbitant cost of treatment in the United States, he has not been able to receive effective treatment.
IASO
BCMA-CAR-T
In July 2023, the BCMA-targeted Equecabtagene Autoleucel Injection developed by IASO Biotech was approved for marketing, specifically for the treatment of relapsed or refractory multiple myeloma adult patients who have undergone at least 3 prior lines of therapy. However, the price is only one-third of the treatment cost in the United States.
After consultation with Director Li Hua and Dr. Zhou Lili from the Hematology Team at Jiahui International Hospital, he decided to undergo this cutting-edge treatment at Jiahui. Throughout the treatment process, he continued working without interruption, only taking leave in the last three weeks for cell infusion, and the entire process went smoothly.
Choosing Jiahui International Hospital for CAR-T treatment not only avoided the hassle of extensive travel but also provided access to international standard medical services, efficient and convenient services, advanced therapies, and state-of-the-art facilities.
Since the approval of Chinese CAR-T therapy
China has established many high-level international CAR-T treatment teams, and more and more foreign and domestic hematologic tumor patients have chosen China for CAR-T treatment, including foreign lymphoma and multiple myeloma patients who have completed treatment and been discharged, as well as many patients from abroad who urgently need CAR-T treatment.
In the future, China will continue to explore innovative concepts and technologies for the clinical application, bringing new hope for cure to more hematologic tumor patients.
���To assess whether the condition is suitable for CAR-T therapy, you can submit Advanced Medicine in China for preliminary evaluation!
Email: doctor.huang@globecancer.com,
WhatsApp: +8613717959070
��� #CAR-T Success Story# ��� #Jiahui International #Cancer Center# ��� #International Collaboration# ���️ #Hope For Cure #Hope for patient #jiahui #cancer treatment
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Breakthrough in Reducing Lupus with Successful Application of CAR-T Dual Target Technology
🌈Breakthrough in Reducing Lupus with Successful Application of CAR-T Dual Target Technology 🌟
Lupus
Lupus