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Chinese Medicine Team Achieves Global Milestone: First Successful Treatment of Pancreatic Cancer Patient with Innovative Dual-Targeted CAR-T Cell Therapy (KD-496)!
🎉 Chinese Medicine Team Achieves Global Milestone: First Successful Treatment of Pancreatic Cancer Patient with Innovative Dual-Targeted CAR-T Cell Therapy (KD-496)!
Dual-Targeted CAR-T
Chinese Medicine
💪The team at the Department of Digestive Oncology, Peking University Cancer Hospital, led by Professor Shen Lin, has accomplished a groundbreaking feat! They have successfully completed the world’s first clinical study using an innovative dual-targeted CAR-T cell therapy (KD-496) for pancreatic cancer. This exciting news stems from their recent completion of the NCT06134960 study.
KD-496
⭐️This study, initiated by investigators (IIT), aims to evaluate the safety and efficacy of KD-496 CAR-T therapy for advanced NKG2DL+ /CLDN18.2+ solid tumors. It is a single-center, open-label, single-arm clinical study designed to explore the potential application of this new therapy in pancreatic cancer treatment.
CAR-T
⚡️On March 4, 2024, Professor Shen Lin’s team completed the infusion of KD-496 CAR-T cells for the first pancreatic cancer patient. The good news is that everything proceeded smoothly, with no adverse reactions reported in the participant, laying a solid foundation for the future application of this therapy.
NKG2DL+ /CLDN18.2+ solid tumors
🌤KD-496 CAR-T therapy targets advanced NKG2DL+ /CLDN18.2+ solid tumors, focusing primarily on pancreatic and gastric cancers, two urgent areas in digestive oncology. Currently, pancreatic cancer treatment primarily relies on surgery, but due to the lack of early symptoms, 80% of patients are often diagnosed at advanced stages, with a 5-year survival rate of less than 6%, necessitating urgent need for new treatment methods. On the other hand, despite advancements in gastric cancer treatment, the prognosis for advanced-stage patients remains bleak, with high incidence and mortality rates.
Hope
✨The success of Professor Shen Lin’s team marks a significant milestone in the medical field, offering new hope for patients with digestive system tumors. With the continued refinement and dissemination of this therapy, we hope to provide more effective treatment options for more patients, enabling them to regain new life. Let us look forward to future advancements, contributing to the development of medical technology and human health together!
🌈We can help all international patients come to China to receive anticancer therapies such as CAR-T, TILs, and cancer vaccines.
🌦We have access to medical resources from all cancer hospitals in China and can assist patients in receiving treatment from the best and top-tier oncologists in the CHINA.
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#ChineseMedicine #CancerTreatment #CART #PancreaticCancer #NewTherapy #Hope #ChineseMedicine #CARTCellTherapy #KD496 #PekingUniversityCancerHospital
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The Chinese CAR-T therapy achieves a miraculous cure for advanced liver cancer, creating wonders in the field of cellular treatment for solid tumors.
The Chinese CAR-T therapy achieves a miraculous cure for advanced liver cancer, creating wonders in the field of cellular treatment for solid tumors.🌞🌞
🥰Surviving Against the Odds: A Chinese Doctor’s Journey with Liver Tumor🥰
Zou began his career in 1989 and has dedicated 30 years as an obstetrician-gynecologist, tirelessly working on the frontline of clinical care.
⭐️”One afternoon, I felt excruciating pain in my right shoulder while sitting in the office. It turned out I had three massive tumors on my liver. At that moment, I had no idea that my life had entered a countdown,” recalls Dr. Zou.⭐️
⭐️”Dr. Zou is in the advanced stage of liver cancer, with metastasis to the lungs,” urgently declared Prof.Shi as he convened a team of experts to consult on Dr. Zou’s condition.⭐️
⭐️ “With conventional treatment, the survival period is typically 3-6 months. Even with surgery, there’s no hope,” stated Prof.Shi.⭐️ Dr. Zou, a doctor himself, continued to ponder work matters, but colleagues and loved ones were tirelessly searching for any possible cure.
⭐️”Prof.Shi mentioned this immunotherapy, an antibody treatment,” said Dr. Zou’s wife.⭐️
Antibody therapy, specifically Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T), is a novel precision-targeted treatment for tumors. Using genetic engineering, T-cells are activated and equipped with a guided navigation device called CAR (Chimeric Antigen Receptor), transforming ordinary warriors into super soldiers known as CAR-T cells. These cells specifically recognize and efficiently eliminate tumor cells, achieving the goal of treating malignant tumors.
Fortunately, Dr. Zou’s health indicators perfectly matched the criteria for CAR-T therapy, providing him with a chance to defy death.
⭐️”In the early stages, I needed treatment every two weeks. Finally, after five or six sessions, my cancer cells started degenerating and liquefying. By now, the last and originally largest tumor has significantly liquefied and been absorbed,” Dr. Zou said.⭐️
⭐️”A miracle happened. We have taken a significant step in overcoming liver cancer in humans,” Prof.Shi added.⭐️
As the treatment gradually took effect, Dr. Zou’s health improved, allowing him to resume his daily work. After completing the treatment cycle, Dr. Zou once again donned the white coat, transitioning from patient to doctor.
In his heart, a stronger belief in the sincerity towards the medical profession and the health of patients emerged.
#SurvivorStories #MedicalMiracle #Inspiration #CancerSurvivor #CARTTherapy #AgainstAllOdds #HealthJourney #BelieveInMiracles #advancedmedicineinchina #chinesemedicine