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22 Days from Desperation to Rebirth! Chinese CAR-T Therapy Creates Survival Miracle for Thai Multiple Myeloma Patient
22 Days from Desperation to Rebirth! Chinese CAR-T Therapy Creates Survival Miracle for Thai Multiple Myeloma Patient
In July 2017, 58-year-old Ms. M was diagnosed with multiple myeloma. After receiving treatments at the best hospital in Thailand, including PCD, DVD, bortezomib and lenalidomide, autologous hematopoietic stem cell transplantation. The disease rapidly relapsed. Local doctors informed Ms. M’s family that apart from palliative care, they were powerless.
Just as Ms. M was in dire straits, on June 30, 2023, the world’s first fully human BCMA CAR-T therapy – Equecabtagene Autoleucel, was shockingly launched in China, becoming a lifesaving straw for her. Ms. M and her family decided to seek treatment in China.
In September 2023, Professor Li Ping’s team at Shanghai Tongji Hospital developed a personalized Equecabtagene Autoleucel(BCMA CAR-T) therapy plan for Ms. M. What shocked everyone was that the examination results 22 days after CAR-T treatment showed that Ms. M had achieved hematologic CR, meaning that no cancer cells were detected in her blood. Her pain and anemia were also reversed. It was simply a miracle!
Reference：
[1]Yuting Yan, et al. Blood Adv. 2019 Oct 8;3(19)：2895-2904.
[2] 2023 IMS. P-290.
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22 Days from Desperation to Rebirth! Chinese CAR-T Therapy Creates Survival Miracle for Thai Multiple Myeloma Patient
22 Days from Desperation to Rebirth! Chinese CAR-T Therapy Creates Survival Miracle for Thai Multiple Myeloma Patient
Patient story
In July 2017, 58-year-old Ms. M was diagnosed with multiple myeloma. After receiving treatments at the best hospital in Thailand, including PCD, DVD, bortezomib and lenalidomide, autologous hematopoietic stem cell transplantation. The disease rapidly relapsed. Local doctors informed Ms. M’s family that apart from palliative care, they were powerless.
Just as Ms. M was in dire straits, on June 30, 2023, the world’s first fully human BCMA CAR-T therapy – Equecabtagene Autoleucel, was shockingly launched in China, becoming a lifesaving straw for her. Ms. M and her family decided to seek treatment in China.
In September 2023, Professor Li Ping’s team at Shanghai Tongji Hospital developed a personalized Equecabtagene Autoleucel(BCMA CAR-T) therapy plan for Ms. M. What shocked everyone was that the examination results 22 days after CAR-T treatment showed that Ms. M had achieved hematologic CR, meaning that no cancer cells were detected in her blood. Her pain and anemia were also reversed. It was simply a miracle!
Reference：
[1]Yuting Yan, et al. Blood Adv. 2019 Oct 8;3(19)：2895-2904.
[2] 2023 IMS. P-290.
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A New Chapter in Survival! A Quadruple Drug Combination Opens Up a New Treatment Pathway for Multiple Myeloma Patients
🌟 *A New Chapter in Survival! A Quadruple Drug Combination Opens Up a New Treatment Pathway for Multiple Myeloma Patients.* 🌟
💪Multiple myeloma has long been a challenging disease to treat, but with the development of new drugs and immunotherapy, the prognosis for MM patients has improved significantly. Now, a new study has opened up a fresh avenue of treatment for us!
#NEJM, #Multiple myeloma
🔬 **Research Findings**
According to a report in the New England Journal of Medicine (NEJM), a study has demonstrated that daratumumab, targeting the CD38 molecule, combined with VRd (referred to as the D-VRd regimen), shows promising safety and efficacy for newly diagnosed multiple myeloma patients eligible for transplantation (NDMM).
📊 **Study Results**
After a median follow-up of 47.5 months, the D-VRd group had a lower risk of disease progression or death compared to the VRd group. At 48 months, the progression-free survival rate for the D-VRd group reached 84.3%, significantly higher than the 67.7% in the VRd group (P＜0.001). Additionally, the D-VRd group had significantly higher rates of complete response and deeper response compared to the VRd group, with a higher MRD negativity rate as well.
💡 **Conclusion**
This study indicates that the D-VRd regimen brings significant benefits to newly diagnosed multiple myeloma patients, including prolonged progression-free survival, higher rates of response, and MRD negativity. This combined therapy has the potential to become a new frontline treatment for multiple myeloma, offering patients longer survival and improved quality of life!
🔍 **Learn More**
For more information on the latest treatment advances and research findings in multiple myeloma, stay tuned to our page!
📚We can help all international patients come to China to receive anticancer therapies such as CAR-T, TILs, and cancer vaccines.
We have access to medical resources from all cancer hospitals in China and can assist patients in receiving treatment from the best and top-tier oncologists in the CHINA.
doctor.huang@globecancer.com
WhatsApp+8613717959070
#MultipleMyeloma #NewTreatmentApproach #HealthScience #MedicalResearch